Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment

B Löwe, RL Spitzer, JBW Williams, M Mussell… - General hospital …, 2008 - Elsevier
OBJECTIVE: To determine diagnostic overlap of depression, anxiety and somatization as
well as their unique and overlapping contribution to functional impairment. METHOD: Two
thousand ninety-one consecutive primary care clinic patients participated in a multicenter
cross-sectional survey in 15 primary care clinics in the United States (participation rate,
92%). Depression, anxiety, somatization and functional impairment were assessed using
validated scales from the Patient Health Questionnaire (PHQ)(PHQ-8, eight-item depression …
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